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Histamine Dumping: Exploring its Symptoms, Causes, and How to Find Relief

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Uncovering Why Histamine Dumping Happens and How to Make it Stop

Have you ever experienced those moments when your body throws a surprising curveball, leaving you wondering what the heck is going on??

Maybe you’ve found yourself questioning why your cheeks are so warm or why you can’t get rid of your headaches.

What’s really fascinating is that these signs might not be coincidental; they could be your body’s direct way of highlighting an underlying health concern, all thanks to a process called histamine dumping.

Our goal here is to dive into the details around histamine dumping, starting with a simple understanding of what it entails and why it’s relevant. We’ll also explore how it might be linked to the symptoms you’ve been dealing with. Let’s uncover the connections between your mysterious symptoms and the scientific aspects of histamine.


What is histamine dumping?

Histamine, a crucial compound in our body, plays a key role in several vital functions. It acts as a messenger, managing responses to allergens, controlling stomach acid production, and even influencing sleep patterns.[1] However, when our body struggles to process and maintain histamine levels properly, we encounter histamine dumping.

Histamine dumping happens when there’s an issue with breaking down histamine and keeping its levels balanced. Typically, certain enzymes, such as diamine oxidase (DAO) and histamine N-methyltransferase (HNMT), break down histamine and prevent its accumulation.[2] However, in cases of histamine dumping, these enzymes might not work well, or there might not be enough of them. This leads to extra histamine staying in the body,  ultimately bringing about your uncomfortable symptoms.


Common Symptoms of Histamine Dumping

Common Symptoms of Histamine Dumping

Histamine dumping brings about a range of uncomfortable symptoms that can vary in intensity from person to person. These can include: [3]

  • Itching
  • Hives
  • Redness and flushing of the skin
  • Bloating
  • Acid reflux
  • Irregular bowel movements
  • Fatigue
  • Low energy
  • Persistent and nagging headaches
  • Stuffy or runny nose
  • Rapid heartbeats
  • Increased anxiety
  • Irritability
  • Mood swings
  • Body aches or chills
  • Sleep disturbances

The interesting part is that while these symptoms may differ in severity, they all link back to histamine dumping. For some, it might be a mild annoyance; for others, it could be a more intrusive disruption. This variability adds to the complexity of histamine dumping, making it essential for individuals to identify their unique symptom profiles for effective management.

Why are histamine dumping symptoms worse at night?

Histamine dumping at night is relatively common because the body naturally releases more histamine at night and after meals. Late-night histamine-rich meals, reduced histamine metabolism during sleep, and stress-related hormone changes can all increase histamine release.


Causes and Triggers of Histamine Dumping

Histamine dumping usually happens because of disruptions that upset the delicate balance of histamine metabolism and regulation within the body. The DAO and HNMT enzymes usually act as the body’s natural regulators, ensuring that histamine levels remain in check. But when this system is disrupted, histamine breakdown can hit a snag.

In essence, histamine dumping occurs when the scales tip and the body’s ability to metabolize and regulate histamine becomes compromised. This disruption can stem from various factors, including genetic predispositions, environmental influences, and other underlying health conditions.

Potential causes and triggers of histamine dumping include: [4]

  • Enzyme Deficiencies: Inadequate levels or dysfunction of DAO and HNMT can hinder the breakdown of histamine, leading to its accumulation in the body.
  • Genetic Predisposition: Genetic variations can influence the efficiency of histamine-metabolizing enzymes or alter histamine receptor sensitivity, making some people more susceptible to histamine intolerance and histamine dumping.
  • Environmental Factors: Exposure to allergens, pollution, dietary choices, mold, and volatile organic compounds (VOCs), especially in certain environments, can worsen the occurrence of histamine dumping. These environmental conditions can trigger histamine release or disrupt its natural regulatory mechanisms, making it challenging for the body to manage histamine levels effectively.
  • Histamine-Rich Foods: Consuming foods naturally high in histamine, such as aged cheeses, processed meats, and fermented products, can contribute to elevated histamine levels in people with histamine intolerance.
  • Alcohol: Alcohol consumption can disrupt histamine metabolism and increase histamine levels, triggering histamine dumping episodes.
  • Stress: Physical and emotional stress can prompt the release of histamine as part of the body’s stress response, exacerbating histamine levels and intensifying symptoms.
  • Underlying Health Conditions: Certain health conditions, such as mast cell disorders and gastrointestinal disorders, can contribute to histamine dumping by disrupting the body’s histamine regulation mechanisms.
  • Medications: Some medications, particularly non-steroidal anti-inflammatory drugs (NSAIDs) and antibiotics, can interfere with histamine breakdown and contribute to histamine accumulation.


Diagnosing Histamine Dumping

Histamine dumping can cause various uncomfortable symptoms ranging from skin reactions to digestive issues. These symptoms can easily resemble other health problems, making it tricky to diagnose accurately.

This shared symptom presentation can lead to confusion or delays in diagnosis, with many people undergoing numerous tests only to find their symptoms persist without a clear explanation. There is also no standardized test for histamine intolerance. Instead, a comprehensive assessment involving symptom tracking, dietary adjustments, and controlled challenges might be needed to piece together the puzzle and achieve an accurate diagnosis. Keeping an open mind and being patient with yourself is essential as you work to uncover and treat the root cause behind your symptoms.


How to Alleviate and Manage Histamine Dumping Symptoms

How to Alleviate and Manage Histamine Dumping Symptoms

Histamine dumping symptoms can be distressing, but there are various strategies that you can adopt to help alleviate and manage your discomfort. While it’s important to talk with your healthcare provider for personalized guidance, here are some general approaches to help:

Dietary Modifications

  • Low-Histamine Diet: Reduce histamine-rich foods like aged cheeses, processed meats, and fermented products. Opt for fresh, unprocessed foods instead.
  • Anti-inflammatory Foods: Include foods rich in antioxidants, such as fruits, vegetables, and omega-3 fatty acids, which help mitigate inflammation.


  • Quercetin: A natural antihistamine found in foods like apples and onions, quercetin can help manage histamine release.
  • Vitamin C: Known for its antihistamine properties, vitamin C can support the body’s response to histamine.

I recommend Optimal Reset Historelief, which contains both quercetin & C, plus other histamine-supporting ingredients, to support healthy histamine levels and your immune system.

Lifestyle Adjustments

  • Stress Management: Practice relaxation techniques like deep breathing, meditation, or vagal toning exercises to reduce stress-induced histamine release.
  • Sleep Hygiene: To ensure a good night’s sleep, it’s essential to establish and stick to a regular sleep routine. This means going to bed and waking up at the same time each day, even on weekends. Additionally, creating a sleep-conducive environment is key. Make your sleep space comfortable and relaxing by keeping your bedroom cool, dark, and quiet. Minimize exposure to screens, such as phones and computers, before bedtime, as the blue light emitted from these devices can disrupt your body’s natural sleep-wake cycle. Lastly, try to unwind before bedtime with calming activities like reading, taking a warm bath, or practicing relaxation techniques to prepare your mind and body for a restful night’s sleep.

Gut Health

  • Low Histamine Probiotics: Support gut health with probiotic-rich foods or supplements to improve digestion and potentially reduce histamine production.

Hydration and Hygiene

  • Stay Hydrated: Drinking enough water can help flush excess histamine from the body. But it’s not just about drinking water; maintaining the right electrolyte balance is crucial. Electrolytes, such as sodium, potassium, and magnesium, ensure efficient hydration. Try my favorite electrolytes to support your histamine management.
  • Skin Care: Use gentle skincare products to avoid aggravating skin reactions.

Remember, every person’s response to histamine dumping is unique! Finding the right combination of strategies that work for you might require some trial and error. Seeking guidance from a healthcare provider experienced in histamine intolerance is crucial to tailor a plan that addresses your specific needs.


Take Charge of Histamine Dumping

When we talk about histamine dumping, one truth stands out: knowledge holds the key to relief!

So, while navigating histamine dumping may be complex, armed with insights into dietary adjustments, stress management, and lifestyle changes, you can actively work towards alleviating discomfort!

I know it’s possible because I did it!

How frustrating it feels to be sick all the time and hear from doctors that “there’s nothing wrong with you.” I went through it for years. I was exhausted, gaining weight, had terrible migraines, and experienced numerous food sensitivities.

But when I pieced together the puzzle of my histamine intolerance, it was life-changing. Today, I can eat most foods without problems and enjoy regular workouts. Plus, most of my symptoms are gone because I addressed the underlying root causes of my inability to break histamine down properly!

You know what? You can absolutely find relief from those puzzling and debilitating histamine intolerance symptoms, and I’d love to share with you how I did it myself!

Discover what is driving your histamine intolerance symptoms and how to support your body by scheduling a consultation today.

Not sure if you’re ready for a consultation? Try our Histamine Reset Online Program to begin healing your body on your time. This is the exact plan I give my patients that I work with one-on-one, and I know it works!



  1. “Histamine Intolerance—The More We Know the Less We … – NCBI.” 29 Jun. 2021, Accessed 22 Aug. 2023.
  2. “Histamine: A molecular double agent | Protein Data Bank in Europe.” 1 Jun. 2023, Accessed 22 Aug. 2023.
  3. “Histamine Intolerance Originates in the Gut – PMC – NCBI.” 12 Apr. 2021, Accessed 22 Aug. 2023.
  4. “Histamine Intolerance: The Current State of the Art – PMC – NCBI.” 14 Aug. 2020, Accessed 22 Aug. 2023.



Hi, I am Dr. Becky Campbell. I work with men and women who’ve had a health set back and are willing to do whatever it takes to reach optimal health so they can perform their best in their careers and be fully present with their family again.