How I Improved My Detoxification with an Infrared Sauna

As many of you know, I’ve experienced numerous chronic health issues, including thyroid imbalances linked to gut problems, heavy metals, and viruses, for most of my life.

As a child, heat intolerance was my constant companion, leading to fainting spells, headaches, and sometimes, unexplained hives. Consuming histamine-rich foods triggered tingling sensations and profound fatigue. 

Over time, my symptoms escalated to migraines, vertigo, heart palpitations, anxiety, panic attacks, acid reflux, seborrheic dermatitis, and low blood pressure. And if that wasn’t enough, during the peak of my thyroid and gut issues in my early twenties, nearly every food elicited negative reactions. 

Ultimately, addressing my hypothyroidism, excess cortisol, leaky gut, candida, and parasites helped me find some improvement. But, even after all of that, many of my symptoms persisted until I began piecing together my histamine intolerance and mast cell activation story. 

What you may not know is that during all of that, I also struggled with extreme chemical sensitivity, and I was a horrible detoxer. 

I mean, it was bad! 

I couldn’t go into stores without being overwhelmed by all the smells. I would have to run in, holding my breath, knowing that I’d likely have a headache by the time I got back to the car. I would get more and more dizzy and just feel completely off with each minute that I was in there.

And no wonder many of my symptoms lingered for so long; my body could literally not detox all of the chemicals out. Even my mold tests came back negative because I could not push the mold toxins into my urine. 

So, what’s changed?

After a great deal of research and several suggestions from friends and colleagues, I found my number one health hack – an infrared sauna. 

Regularly using an infrared sauna is the one thing that has moved the needle the most with my health. 

Now, I can walk through a store and browse without feeling so weird!

Plus, I have been able to detox from many of the toxins in my body – mold, mercury, excess histamine – and I rarely experience mast cell activation flair-ups!

Now, I’m ready to share all the research, suggestions, and more of my personal story with you!

Types of Saunas

Let’s start by talking about all things saunas. You’re probably familiar with some of the more popular types of saunas, like those available at your gym or spa.

Here are the three main types of saunas:

• Steam Sauna: Common in fitness centers, these saunas use steam generated electronically to build the heat. These saunas rely on high heat, which can be tough for those with Mast Cell Activation Syndrome (MCAS) or Histamine Intolerance. Plus, steam brings humidity into the mix, which can mean mold.

• Heated Rock Sauna: This is your traditional spa sauna, where you pour water over hot rocks to create steam. They share the same drawbacks of high temperatures and potential humidity issues with other steam saunas – something you’d want to avoid with sensitivities.
• Dry Sauna: Unlike the first two, dry saunas don’t add humidity with water, which is great for avoiding mold problems, but the high temperatures might not be ideal if you’re sensitive to heat or prone to flares.

Here’s what changed the game for me: Infrared Sauna.

Unlike the others, infrared saunas work efficiently at lower temperatures. 

Infrared waves actually penetrate your skin, which heats your core temperature without heating the room. This heating method makes infrared saunas a game changer for those with MCAS and Histamine Intolerance, especially if heat sensitivity is an issue. 

On top of that, infrared saunas do not produce any humidity, meaning no worries about mold growth.  

Infrared Sauna Therapy for MCAS and Histamine Intolerance

At its core, sauna therapy includes a range of physiological responses that contribute to the body’s detoxification process. The heightened ambient temperature within a sauna promotes increased heart rate and improved circulation, enhancing the delivery of oxygen and nutrients to tissues. 

While research on saunas specifically tailored to MCAS and Histamine Intolerance is limited, anecdotal evidence suggests that many people (including myself) find relief in this therapeutic approach.

What makes an infrared sauna ideal for MCAS and Histamine Intolerance?

Let’s start by breaking down the concept of infrared light – it’s a slice of the sun’s spectrum crafted into a sauna experience.

Unlike traditional saunas that warm the air first, infrared saunas cut to the chase, getting absorbed by the body to elevate your core temperature. 

This distinction is crucial for those sensitive to heat, offering a gentler and more comfortable experience than traditional saunas' intense heat. 

Think of our bodies as solar panels in need of light for survival. Infrared steps in, activating our internal solar panels contributing to cellular regeneration as water and mitochondrial molecules respond to the infrared beat.

Let’s explore the tailored benefits of the three bands within the infrared spectrum:

• Far Infrared: This superhero band, with its cool wavelength, penetrates the body, offering benefits such as detoxification, cardiovascular support, and immune system enhancement. For those with MCAS and Histamine Intolerance, the gentler warmth of far infrared minimizes the risk of triggering adverse reactions.

• Mid-Infrared: Slightly hotter, this band proves effective for immunity, weight loss, and pain reduction. Its role in post-workout recovery is particularly valuable if you are managing a health condition while trying to stay active. 
• Near Infrared: Often dubbed the ‘vanity wavelength,’ near-infrared is a discreet performer that goes deep without causing discomfort. For those with sensitivities, this band stimulates mitochondria, promotes collagen production, and contributes to skin health – achieving aesthetic benefits without the intensity of traditional sauna heat.

Near-infrared, which can reach tissues up to 5 centimeters deep, stimulates mitochondria, fostering cellular rejuvenation. Simultaneously, the visible red light available on many infrared saunas does not penetrate as deeply but does contribute to skin health by helping reduce oxidative stress. 

This combined approach targets aesthetic concerns and promotes overall skin well-being by delving into the depths of tissue to enhance cellular functions and support skin vitality.

Because the focus of infrared sauna therapy extends beyond mere heat, it’s a great choice for those managing the intricacies of MCAS and Histamine Intolerance. 

Infrared Sauna Benefits

In addition to the benefits associated with each light band, research indicates a wide range of health benefits associated with infrared saunas, including:

• Inflammation Reduction: Infrared saunas are effective in lowering inflammation levels.

• Antioxidant-Like Effects: Acting similarly to antioxidant nutrients, they contribute to overall cellular health.

• Cell Healing Activation: Increased blood flow from the infrared sauna activates cell healing cycles.

• Cardiovascular Support: Regular use can reduce the risk of heart disease and other cardiovascular issues.

• Metabolism Boost: Infrared saunas can boost metabolism and aid in calorie burning.

• Wound Healing: The increased production of collagen and elastin helps heal wounds.

• Detoxification: Facilitates the removal of toxins from the body, including mold toxins, chemicals, and metals. 

• Immune System Support: Infrared saunas contribute to immune system support by helping eliminate microbes, which can be beneficial in conditions like Lyme or other tick-borne illnesses.

• Improved Sleep: Linked to better sleep quality, promoting relaxation and addressing sleep-related issues.

• Stress Reduction: The soothing effects of infrared light contribute to stress reduction, promoting a sense of calm and well-being.

• Mood Enhancement: The release of endorphins triggered by infrared light can lead to an uplift in mood, potentially assisting in managing symptoms of depression or mood disorders.

Sauna Benefits for MCAS and Histamine Intolerance

As you can see, sauna therapy offers a ton of health benefits, and even though research on mast cells, histamine intolerance, and sauna is limited, promising findings from two notable studies provided some key insights:

1. A 2013 study suggested that repeated sauna use may benefit individuals with allergic rhinitis, a condition often linked to mast cell activation.
2. In 2014, a case study revealed the efficacy of sauna in alleviating severe chronic itching, commonly associated with mast cell activation and heightened histamine levels.

Beyond these specific studies, sauna usage has demonstrated broader benefits for those with MCAS or Histamine Intolerance:

• It supports the nervous system and relaxation, both crucial for addressing and managing MCAS and Histamine Intolerance.
• It positively impacts immune system functioning, indirectly benefiting mast cells connected to the broader immune system.
• Aids in toxin removal, including mold toxins – a key trigger for MCAS.
• It benefits various skin conditions like psoriasis and eczema, often correlating with MCAS and histamine intolerance.

Tips for a Safe Infrared Sauna

If you’re thinking about trying an infrared sauna and you’re managing MCAS or Histamine Intolerance, keep these tips in mind to safely incorporate sauna therapy into your routine.

• • Optimal Timing: Consider using the sauna right after a cardio or strength workout. This is what I do! I’m already sweating, so I hop into my sauna to optimize those detoxification pathways. Plus, I find that morning sessions get me energized for the rest of my day.
  • Stay Hydrated: Drink electrolytes while using the sauna to maintain hydration levels and replenish essential minerals lost through sweating.
  • Turn on the sauna when you get in: No need for pre-heating. Far infrared is most efficient when first initiated. So, getting in the sauna while it’s heating ensures optimal absorption of far infrared into the body.

• Start Slow: Begin with shorter sessions and lower temperatures to acclimate your body to the sauna environment. Even brief sessions of 5 or 10 minutes can be beneficial. Gauge your body’s response and gradually increase the duration as tolerated.
• Use this time to multitask: Use your sauna time as an opportunity for habit stacking. Try incorporating meditation, breathwork, stretching, intention setting, or visualization to enhance your overall wellness experience. I like to read a book or listen to a podcast to help me relax.

Because sauna sessions facilitate the movement of toxins out of your body, I recommend using a binder before starting your sauna. 

Binders help collect the toxins the sauna got moving, aiding in their elimination through bowel movements. This proactive step ensures toxins exit the body, preventing their recirculation through the bloodstream.

I also recommend taking glutathione prior to going in the sauna, if you tolerate it. My Liver Love is another great option. (please link to liver love)

Lastly, I can’t say this enough – listen to your body and tailor your sauna sessions to align with your needs and tolerance levels. 

Why I Chose a Sunlighten Infrared Sauna

Selecting the right infrared sauna when struggling with MCAS or Histamine Intolerance can be tricky because some saunas may still induce flares. My exploration led me to consider Sunlighten as a preferable option for those with MCAS and Histamine Intolerance, and here’s why:

• Comprehensive Infrared Wavelengths: Sunlighten encompasses all three essential infrared wavelengths, providing a holistic approach to the therapeutic benefits of infrared sauna sessions.

• Lower Temperatures, Shorter Times: Sunlighten allows you to experience the same health benefits at lower temperatures and in shorter durations. This adaptability carters to the unique sensitivities of those with MCAS or Histamine Intolerance.

• Low EMF Infrared Sauna: With third-party testing validation, Sunlighten ensures low electromagnetic field (EMF) exposure during sauna sessions, contributing to a safer and more tolerable experience.

• No Chemical Off-Gassing: Sunlighten saunas are designed without the presence of chemical off-gassing, minimizing potential triggers for those of us with heightened sensitivities.
• Sustainably Made: Sunlighten emphasizes sustainability using environmentally friendly materials.

And the best news of all – now you can experience the unparalleled benefits of a Sunlighten sauna with my special discount. 

For a limited time, Sunlighten is offering

• Up to $600 off cabin models
• $250 off the solo unit (portable & cost-effective unit)

To take advantage of these special offers, follow these steps:

Contact Sunlighten Online and mention the Dr. Becky Campbell discount, or call them directly and let them know you’re a part of the Dr. Becky community.

Don’t miss this opportunity to enhance your wellness journey and access my favorite health hack – a quality sauna from Sunlighten!

 

Resources

1. "Temp Temp CORE TEMPERATURE STUDY." https://infraszauna.hu/wp-content/uploads/2018/10/solo-test-results.pdf. Accessed 20 Nov. 2023.
2. "Far infrared radiation (FIR): its biological effects and medical ... - NCBI." 16 Oct. 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699878/. Accessed 20 Nov. 2023.
3. "Biological effects and medical applications of infrared radiation - NCBI." 13 Apr. 2017, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505738/. Accessed 20 Nov. 2023.
4. "A Controlled Trial to Determine the Efficacy of Red and Near ... - NCBI." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926176/. Accessed 20 Nov. 2023.
5. "Raising body temperature relieves depression symptoms, small ...." 16 May. 2016, https://medicalxpress.com/news/2016-05-body-temperature-relieves-depression-symptoms.html. 
6. "Effects of far-infrared sauna bathing on recovery from strength and ...." 7 Jul. 2015, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493260/. Accessed 20 Nov. 2023.
7. "Fever and the thermal regulation of immunity - NCBI." 15 May. 2015, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786079/. Accessed 20 Nov. 2023.
8. "Blood, urine, and sweat (BUS) study: monitoring and elimination of ...." https://pubmed.ncbi.nlm.nih.gov/21057782/. Accessed 20 Nov. 2023.
9. "The effect of six-weeks of sauna on treatment autonomic nervous ...." https://pubmed.ncbi.nlm.nih.gov/23859414/. Accessed 20 Nov. 2023.
10. "Beneficial effect of sauna therapy on severe antihistamine-resistant ...." https://www.ima.org.il/filesupload/IMAJ/0/76/38034.pdf. Accessed 20 Nov. 2023.
11. "Sunlighten Sauna EMI Test Document Number: VTE-3200." 20 Jan. 2021, https://assets-us-01.kc-usercontent.com/9832d3f0-685b-0021-9fc3-0a88ee8dfc7a/33164ff5-ea58-4bb9-a3a8-ce35e00dabaf/Low%20EMF%20Test%20Results%20for%20Sunlighten%20Saunas%20by%20Vitatech%20Electromagnetics.pdf. Accessed 20 Nov. 2023.

 

---

by Peter Saydak

Protein: The Critical Role of Protein For Women

Let’s face it—protein is not exactly the life of the dietary party. It doesn’t have the flashy appeal of the latest superfood or the buzz of a trendy new supplement. But don’t let that fool you. 

Protein is the unsung hero of a well-balanced diet, holding everything together like the duct tape of nutrition. It supports muscle growth, aids in repair, and keeps our metabolism humming along smoothly. Without it, well, let’s just say you wouldn’t be able to lift your coffee mug in the morning—let alone your spirits.

For women, protein plays a crucial role at every stage of life, from puberty to menopause. It’s essential for maintaining lean muscle mass, boosting bone health, and keeping our weight management in check. 

But if you’re navigating the tricky waters of MCAS (Mast Cell Activation Syndrome), histamine intolerance, or mold illness, you might find your protein needs – like everything else – are a bit more complicated.

This is where whey protein isolate comes in. 

Think of it as the VIP of protein powders: high-quality, easily digestible, and less likely to cause a poor reaction. 

As someone who’s had their fair share of protein powders and knows the difference between “just okay” and “really effective,” I can tell you that whey protein isolate has become a staple in my own regimen. 

Why?

Because it offers a clean, potent source of protein that’s a little easier on the system.

So, let’s explore why protein is a big deal for women, why whey protein isolate might just be your new best friend, and how you can make it work for you without any of the usual dietary drama.

The Role of Protein in Women’s Health

Alright, let’s get down to the nitty-gritty of protein. What is it, and why should you care? 

In its simplest form, protein is made up of amino acids—the building blocks of life. (1)

Think of amino acids as the Lego bricks that build everything from your muscles and tissues to your hormones and enzymes. Without protein, our bodies would literally fall apart faster than a cheap lawn chair.

Understanding Protein and Its Basic Functions

Protein isn’t just for bodybuilders or those you see hauling around massive tubs of powder at the gym. It’s essential for everyone. 

Here’s a quick rundown of its basic functions: (2, 3, 4, 5, 6)

• Muscle Repair and Growth: Every time you move, lift, or even fidget, your muscles experience tiny tears. Protein swoops in to repair these, making your muscles stronger over time.
• Immune Function: Proteins are crucial for producing antibodies that help fend off illnesses.
• Hormone Production: Hormones are like the body’s text messages, sending instructions to various organs and tissues. Many of these are protein-based.
• Enzyme Activity: Enzymes, which are also proteins, speed up chemical reactions in the body. Think of them as the behind-the-scenes crew that keeps everything running smoothly.

So, what’s in it for you? 

Here are some specific benefits of protein that might make you a believer:

• Supporting Lean Muscle Mass and Metabolism: More muscle mass means a higher resting metabolic rate. In other words, you burn more calories even when you’re binge-watching your favorite shows. Protein helps build and maintain this muscle.
• Enhancing Bone Health: Protein isn’t just about muscles. It’s vital for bone health, too. Adequate protein intake can help prevent osteoporosis and fractures, which is especially important as we age.
• Aiding in Weight Management and Satiety: Ever notice how you’re less likely to snack on junk after a protein-rich meal? That’s because protein helps you feel full longer, aiding in weight management and curbing those late-night cravings.

Protein Needs for Women with MCAS, Histamine Intolerance, and Mold Illness

If you’re experiencing MCAS, histamine intolerance, or mold illness, you know all too well that your body doesn’t exactly follow the usual rules. 

So, how does protein fit into this picture? 

Well, it’s not just about building muscles or staying full – it’s about managing inflammation and bolstering your immune system.

Protein helps in several ways:

• Repair and Recovery: High-quality protein provides the amino acids necessary for repairing tissues and reducing inflammation. Think of it as giving your body the building materials it needs to fix what’s broken.
• Immune System Support: Protein is the building block of many components of the immune system, including antibodies and immune cells. By ensuring you have enough protein, you’re essentially equipping your body’s defense forces with the tools they need to fight off invaders and keep inflammation in check.

Not all proteins are created equal when it comes to MCAS, histamine intolerance, or mold illness. 

Quality matters – a lot.

High-quality protein sources are purer and easier to digest, reducing the risk of triggering adverse reactions. Low-quality proteins often contain additives, fillers, and potential allergens that can exacerbate symptoms.

For a delicious, low-histamine meal packed with high-quality protein, check out this Herb Roasted Turkey Tenderloin with Sage Roasted Apples and Vegetables. Turkey is an excellent source of lean protein and is typically well-tolerated by those with histamine intolerance. Plus, the recipe is free from common triggers and full of flavor.

Why Whey Protein Isolate is Ideal for Woman 

So, what’s all the buzz about whey protein isolate? Let’s break it down.

Whey protein isolate is a high-quality protein derived from milk. During the cheese-making process, whey is separated from the curds and further processed to remove fats and lactose. 

This results in whey protein isolate, which contains a higher concentration of protein—typically around 90% or more—compared to other protein types.

Whey protein isolate is distinct from whey protein concentrate, which contains about 70-80% protein and more fats and lactose. While whey protein concentrate is still a good source of protein, it’s not as pure or protein-dense as the isolate and can be problematic for those with MCAS or histamine intolerance. 

Another type, casein protein, is also derived from milk. It digests more slowly than whey and is great for sustained protein release but not ideal if you need a quick protein boost. Due to its slower digestion and dairy origin, casein also has a higher potential to cause issues, which may trigger symptoms in sensitive individuals.

Plant-based proteins, such as those from peas, hemp, or brown rice, offer an alternative for those avoiding dairy. Still, they often have a lower protein content per serving and commonly contain additives or fillers that can trigger symptoms. In addition, some plant-based proteins can be high in oxalates or other compounds that might not be suitable for those with MCAS or histamine intolerance. 

Benefits of Whey Protein Isolate for Women

Whey protein isolate is a top choice for women looking to boost their health. It’s packed with protein and easy to digest, making it ideal for those dealing with MCAS, histamine intolerance, or mold illness.

High Protein Content and Essential Amino Acids (EEAs): Whey protein isolate boasts around 90% protein per serving, with the highest ratio of essential amino acids (EEAs). This makes it highly effective for muscle repair, growth, and overall health. (7)

Superior Protein Quality and Digestibility: The isolation process ensures high protein quality and easy digestibility, minimizing lactose and fats and making it ideal for sensitive stomachs. (8)

Nutrient Density and Leucine: Rich in essential nutrients and the highest amounts of leucine, whey protein isolate supports muscle protein synthesis (MPS) and lean muscle growth. (9)

Increases Muscle Protein Synthesis (MPS) and Enhances Athletic Recovery: Whey protein isolate promotes MPS, improving lean muscle growth and faster recovery post-exercise. (10)

Promotes Satiety and Weight Management: Protein helps you feel full longer, reducing the likelihood of snacking and aiding in weight management. (11, 12)

Boosts Immune Function: Contains immunoglobulins and lactoferrin to support immune health, which is especially beneficial for those with compromised immunity. (13)

Convenience and Versatility: Easy to incorporate into various diets, whether in smoothies, mixed with water, or added to recipes.

How to Choose the Right Whey Protein Isolate

Selecting the right whey protein isolate is crucial, especially for those managing MCAS, histamine intolerance, or mold illness. 

Here’s what to look for to ensure you’re getting a high-quality, safe product:

• Purity and Quality of Production: Opt for whey protein isolate that is highly purified and produced with minimal processing. This helps reduce the risk of contaminants and ensures you get a product as close to its natural state as possible.
• Avoid Added Ingredients and Allergens: Choose products free from unnecessary additives, fillers, and potential allergens. These can exacerbate symptoms and hinder your overall wellness.

My favorite whey protein isolate option emphasizes high-quality production and purity and avoids adding unnecessary ingredients. Plus, they make a vanilla flavor that’s specifically low in histamine, making it a great choice for those with sensitivities. 

Tips for Incorporating Whey Protein Isolate into Your Diet

Getting whey protein isolate into your daily routine is easier than you think. 

• Try to get around .8-1 gram of protein per pound of DESIRED body weight. 
• Use protein shakes as snacks when you are on the go, or to make a smoothie from home.
• A shake with whey protein isolate can speed up recovery and muscle repair after a workout. 

• 1/2-1 cup frozen blueberries or mango
• 1 cup raw milk (or whatever milk you use)
• Ice
• 1 tbsp. Flaxseed
• 1 scoop protein powder (use vanilla if you want to stay low histamine)

These simple tweaks can help you seamlessly boost your protein intake and support your health goals.

Your Path to Optimal Protein and Wellness

Incorporating adequate protein into your diet is crucial for overall health, supporting everything from muscle growth to immune function. 

Whey protein isolate, with its high protein content, superior digestibility, and low histamine options, stands out as an excellent choice for women – particularly those managing MCAS, histamine intolerance, or mold illness.

For a reliable option, look for a whey protein isolate produced with high standards, like my favorite vanilla flavor, which is low in histamine. 

If you’re looking to tailor your protein intake to your specific needs or need additional support managing your health conditions, I’m here to help. 

Schedule a consultation to get personalized advice and create a plan that aligns with your wellness goals. 

Let’s work together to ensure you get the most out of your dietary choices and feel your best.

 

Resources

1. “Biochemistry, Essential Amino Acids - StatPearls.” NCBI, 30 April 2024, https://www.ncbi.nlm.nih.gov/books/NBK557845/. Accessed 7 August 2024.
2. “Protein – The Nutrition Source.” The Nutrition Source, https://nutritionsource.hsph.harvard.edu/what-should-you-eat/protein/. Accessed 7 August 2024.
3. Wu, Guoyao. “Amino acids and immune function.” PubMed, https://pubmed.ncbi.nlm.nih.gov/17403271/. Accessed 7 August 2024.
4. “Nutrition and Impacts on Hormone Signaling.” The Institute for Functional Medicine, https://www.ifm.org/news-insights/nutrition-impacts-hormone-signaling/. Accessed 7 August 2024.
5. “Protein Hormones and Immunity - PMC.” NCBI, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894894/. Accessed 7 August 2024.
6. “Metabolic networks: enzyme function and metabolite structure.” PubMed, https://pubmed.ncbi.nlm.nih.gov/15193309/. Accessed 7 August 2024.
7. “Protein content and amino acid composition of commercially available plant-based protein isolates.” NCBI, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245118/. Accessed 7 August 2024.
8. “Protein – Which is Best? - PMC.” NCBI, 1 September 2004, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905294/. Accessed 7 August 2024.
9. “The role of leucine and its metabolites in protein and energy metabolism.” PubMed, https://pubmed.ncbi.nlm.nih.gov/26255285/. Accessed 7 August 2024.
10. “Whey protein but not collagen peptides stimulate acute and longer-term muscle protein synthesis with and without resistance exercise in healthy older women: a randomized controlled trial.” NCBI, 9 January 2020, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049534/. Accessed 7 August 2024.
11. “Inulin-type fructans and whey protein both modulate appetite but only fructans alter gut microbiota in adults with overweight/obesity: A randomized controlled trial.” PubMed, https://pubmed.ncbi.nlm.nih.gov/28730743/. Accessed 7 August 2024.
12. “Cocoa and Whey Protein Differentially Affect Markers of Lipid and Glucose Metabolism and Satiety.” PubMed, https://pubmed.ncbi.nlm.nih.gov/26987021/. Accessed 7 August 2024.
13. “Dietary Whey Protein Supplementation Increases Immunoglobulin G Production by Affecting Helper T Cell Populations after Antigen Exposure.” NCBI, 19 January 2021, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835905/. Accessed 7 August 2024.

---

by Peter Saydak

CBD for Mast Cell Activation Syndrome

Living with Mast Cell Activation Syndrome (MCAS) can feel like a constant battle against unpredictable symptoms. From relentless itching and flushing to digestive woes and fatigue, MCAS can significantly impact your daily life. 

Current treatment options often focus on managing flare-ups with antihistamines and other medications, but these may not always provide the relief you seek.

That's why many of my patients with MCAS are turning to complementary therapies to find additional support. 

One option gaining traction is Cannabidiol (CBD), a natural compound found in hemp. While research into CBD for MCAS is still in its early stages, there's a growing body of evidence suggesting its potential to influence the very systems involved in MCAS flare-ups.

In this blog, we’re exploring the science behind CBD and how it might interact with your body to alleviate MCAS symptoms. 

We'll break down the endocannabinoid system's role, how it connects to mast cells, and the potential mechanisms by which CBD could offer relief. We'll also discuss the importance of consulting your healthcare provider and choosing high-quality CBD products. 

So, if you're interested in understanding how CBD might fit into your MCAS management plan, you've come to the right place. 

Let's explore the potential of this natural remedy together.

What is MCAS

Mast Cell Activation Syndrome (MCAS) is a condition where mast cells, a type of immune cell, become overly sensitive and release inflammatory chemicals even in the absence of a major threat. (1)

Imagine these mast cells as the body's alarm system. In MCAS, the alarm goes off way too easily, triggering a cascade of symptoms that can be pretty debilitating.

Mast cells contain granules packed with histamine and other inflammatory mediators. When they become activated, these granules are released (degranulation), causing inflammation and a variety of unpleasant symptoms.

Symptoms of MCAS

MCAS can manifest in a wide range of symptoms affecting various bodily systems, including:

• Skin: Itching, flushing, hives, rashes, swelling (angioedema)
• Respiratory: Wheezing, shortness of breath, nasal congestion, throat tightness
• Gastrointestinal: Abdominal pain, diarrhea, nausea, vomiting, bloating
• Cardiovascular: Rapid heart rate, low blood pressure, lightheadedness
• Neurological: Brain fog, headaches, dizziness, anxiety, fatigue
• Musculoskeletal: Joint and muscle pain, weakness, stiffness
• Systemic: Fatigue, malaise, flu-like symptoms

The unpredictable nature and diverse symptoms of MCAS can make it challenging to diagnose and manage. This is where exploring complementary therapies like CBD comes in.

CBD: A Closer Look

With increasing interest in complementary therapies for MCAS, Cannabidiol (CBD) emerges as a potential option. But what exactly is CBD?

CBD is a naturally occurring compound found in the cannabis sativa plant, particularly abundant in hemp, a variety specifically bred for its low psychoactive properties. 

Unlike its more famous cousin, tetrahydrocannabinol (THC), CBD does not produce the intoxicating "high" associated with marijuana use. CBD is non-psychoactive, meaning you won’t experience any mind-altering effects when consuming CBD products. (2)

This distinction between CBD and THC is crucial. 

While THC may offer some therapeutic benefits, its psychoactive effects can be undesirable for many people. CBD, on the other hand, provides a potential therapeutic approach without altering mental clarity.

The Endocannabinoid System (ECS)

Imagine your body has a built-in regulatory system specifically designed to maintain balance and promote well-being. That's essentially the role of the endocannabinoid system (ECS), a complex network of receptors and signaling molecules naturally produced within us. (3)

The ECS plays a crucial role in regulating various physiological processes, including: (4, 5, 6, 7)

• Inflammation: The ECS helps modulate inflammatory responses, preventing excessive immune system activation.
• Pain: ECS receptors are found throughout the nervous system, influencing pain perception and transmission.
• Immune Function: The ECS plays a role in immune cell activity and helps maintain a balanced immune response.
• Sleep: The ECS is involved in regulating sleep cycles and promoting relaxation.
• Mood: Emerging research suggests the ECS may influence mood and emotional regulation.

The ECS functions by producing its own natural cannabinoids, called endocannabinoids. These endocannabinoids bind to specific receptors located on various cells throughout the body. When activated, these receptors trigger a cascade of signals that influence various physiological functions.

Here’s where things get interesting – cannabinoids, like CBD, share a structural similarity with our body's natural endocannabinoids. While CBD doesn't directly bind to the same receptors, it's believed to interact with the ECS in other ways.

Here's where the potential for CBD to influence health comes in. CBD may:

• Modulate the enzyme activity that breaks down endocannabinoids, allowing them to remain active for longer periods.
• Interact with other receptors in the body, potentially influencing ECS signaling indirectly.
• Influence the production of endocannabinoids by the body.

While the exact mechanisms by which CBD interacts with the ECS are still being explored, this potential interaction offers a framework for understanding how CBD might influence various physiological processes, including those relevant to MCAS.

CBD for MCAS Symptom Management

While the exact mechanisms remain under investigation, pre-clinical research suggests CBD might hold promise for MCAS patients due to its potential influence on several key areas:

1. Anti-inflammatory Properties and Immune Modulation:
   MCAS is characterized by excessive inflammation. Studies suggest CBD may possess anti-inflammatory properties. For example, research indicates CBD might influence the activity of cytokines, signaling molecules involved in the inflammatory response. (8) Additionally, CBD might interact with the immune system, potentially promoting a more balanced immune response. (9)
2. Mast Cell Stabilization - Potential for Reduced Histamine Release: Mast cells are central players in MCAS, and their activation leads to histamine release, triggering various symptoms. Some studies suggest CBD might influence mast cell function. For instance, preliminary research indicates CBD may interact with certain receptors or enzymes involved in mast cell activation and histamine release. (10)
3. Impact on Gut Health: There's growing interest in the gut-mast cell connection, and some MCAS patients experience digestive issues. Early research suggests CBD might positively influence gut health by promoting beneficial gut bacteria and reducing inflammation in the gut lining. (11) While the link between CBD and gut health in MCAS specifically needs further investigation, it's an interesting area to explore.

The research on CBD and its potential benefits for MCAS is still in its early stages, but the initial findings are encouraging. The potential impact on gut health, where some MCAS symptoms originate, adds another layer of intrigue. As research continues to evolve, CBD may become a valuable tool in the comprehensive management of MCAS.

Exploring CBD with Cured Nutrition

Now that we’ve talked about the potential of CBD for MCAS management, I want to share some of my favorite CBD products from Cured Nutrition. 

I liked Cured Nutrition specifically because of its focus on providing high-quality, third-party-tested products. This helps ensure that you know exactly what you’re consuming. In addition, its product range offers a variety of options to suit your needs and preferences. 

Here are three options that make a good starting point when exploring CBD or MCAS:

The Sleep Bundle: This bundle features Night Caps and Zen, two powerful products that work synergistically to promote deep, restorative sleep. Night Caps blend full-spectrum CBD with adaptogens like reishi and magnesium to calm the nervous system, reduce inflammation, and ease you into sleep, while Zen combines functional mushrooms and adaptogens with CBD to reduce stress and anxiety, supporting a peaceful transition to sleep. Together, they ensure you wake up refreshed and ready to tackle the day.

Serenity Gummies: For those who prefer a tasty option, Serenity Gummies are a delicious and convenient way to manage stress and anxiety, especially for those dealing with MCAS. Infused with broad-spectrum CBD, L-theanine, and ashwagandha, these gummies work to calm the nervous system, reduce inflammation, and promote a balanced mood. Whether you're facing a hectic day or need help unwinding in the evening, Serenity Gummies offers a natural solution to keep you centered and calm without drowsiness. They’re an ideal daily companion for maintaining emotional balance and supporting overall well-being.

Relief Bundle: This is a powerful duo designed to tackle pain and inflammation, making it a favorite among patients managing MCAS. This bundle includes CBD Salve and Full Spectrum Raw Oil, two potent products that work together to provide targeted relief and overall support. The CBD Salve combines full-spectrum CBD with a blend of natural herbs and essential oils to deliver soothing, localized pain relief directly where you need it most. The Full Spectrum Raw Oil offers systemic relief by reducing inflammation and promoting overall balance in the body. Together, they offer a comprehensive approach to managing pain, helping you stay active and comfortable throughout the day. 

CBD for MCAS Management

While research on CBD for MCAS is ongoing, the potential for its anti-inflammatory, immune-modulating, and mast cell stabilizing properties offers hope. The early studies, combined with the potential impact on gut health, suggest CBD could be a valuable tool in managing MCAS symptoms.

Finding the right approach for you is key. I've shared some of my favorite CBD options from Cured Nutrition, but remember, everyone's experience is unique. Cured Nutrition offers a variety of high-quality CBD products to support your exploration.

Ready to take control and develop a personalized plan for managing your MCAS?

Schedule a consultation to discuss your specific needs and explore how CBD, along with other strategies, might fit into your comprehensive plan. 

We can help you navigate your options and create a roadmap toward managing your MCAS.

 

Resources

1. “Mast Cell Activation Disorders - PMC.” NCBI, 30 January 2021, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911219/. Accessed 12 July 2024.
2. “Frequently Asked Questions about Conducting Research with Cannabis and Hemp.” National Institute on Drug Abuse, 12 February 2024, https://nida.nih.gov/research/resources-grants-contracts/faqs-conducting-research-with-cannabis-hemp. Accessed 12 July 2024.
3. Kunos, George. “Modulating the endocannabinoid system in human health and disease: successes and failures.” NCBI, 22 April 2013, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684164/. Accessed 12 July 2024.
4. “The endocannabinoid system and pain.” PubMed, https://pubmed.ncbi.nlm.nih.gov/19839937/. Accessed 12 July 2024.
5. “Endocannabinoids and immune regulation - PMC.” NCBI, 7 April 2009, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044336/. Accessed 12 July 2024.
6. “Cannabinoids, Endocannabinoids and Sleep - PMC.” NCBI, 22 July 2020, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388834/. Accessed 12 July 2024.
7. “Review of the Endocannabinoid System.” PubMed, https://pubmed.ncbi.nlm.nih.gov/32980261/. Accessed 12 July 2024.
8. “Antioxidative and Anti-Inflammatory Properties of Cannabidiol.” NCBI, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/. Accessed 12 July 2024.
9. Almogi, Osnat. “Cannabis, the Endocannabinoid System and Immunity—the Journey from the Bedside to the Bench and Back.” NCBI, 23 June 2020, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352399/. Accessed 12 July 2024.
10. “Immunomodulatory actions of cannabinoids: Clinical correlates and therapeutic opportunities for allergic inflammation.” NCBI, 1 February 2024, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918686/. Accessed 12 July 2024.
11. “Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis.” NCBI, 6 December 2011, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232190/. Accessed 12 July 2024.

 

---

by Peter Saydak